PAHO’s ProVac is an initiative originally launched in 2004 and relaunched in 2022, to provide technical cooperation for the promotion of evidence-based decision-making prior the introduction of new vaccines. ProVac currently focuses on pneumococcal, rotavirus, human papillomavirus (HPV), and influenza vaccines. In the near future, ProVac plans to include other priority vaccines in its toolkit for decision-making support at country level.
You can access the ProVac resources below and a document library here.
UNIVAC is a single universal vaccine impact and cost-effectiveness decision support model with a standardized, accessible Excel-based interface and a familiar set of input steps and outputs. Input estimates of age-specific disease burden, age/dose-specific vaccine coverage, and effectiveness allow for a simple evaluation of direct vaccination impact on health outcomes.
COSTVAC is an Excel-based toolkit that provides structured guidance on how to estimate the cost of routine immunization from a sample of health facilities and administrative levels of the health system. This toolkit provides guidance on sampling, survey instrument development and administration, and calculations.
Module 1. Introduction to the ProVac Initiative
Module 2. Introduction to evidence-based decision-making on immunization
Module 3. Introduction to vaccine economics
Introduction to vaccine economics: University of Hong Kong
JSPH open courseware (Teaching Vaccine Economics Everywhere)
Estimating cost of illness from primary data collection – Decade of Vaccine Economics (DOVE) learning modules
Module 4. Immunization program costing
Common approach for the costing and financing analyses of routine immunization and new vaccine introduction costs
JSPH open courseware (Teaching Vaccine Economics Everywhere)
WHO Economics of immunization: a guide to the literature and other resources
Module 5. UNIVAC – A universal model for vaccines cost-effectiveness analyses
DALYs explained
Consolidated Health Economic Evaluation Reporting Standards – CHEERS Checklist
Cost-Effectiveness Article Checklist – ProVAC CEA Article Checklist
Module 6. COSTVAC – Support for immunization program costing
Overview of COSTVAC Download Tools Page
Installation Instructions
Orientation on Data Collection Interface
Practice Data Collection Interface
Aggregation of Collected Data
Making results tables from COSTVAC
Module 7. Communicating the evidence to key stakeholders
