TVEE module: Economic Evaluation

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Economic evaluation studies are conducted to determine what, when and how to introduce new vaccines or which implementation approach/strategy would achieve better and effective coverage. This course will enable students to have a solid introduction to the theory, methods, and application of economic evaluation in health care with a specific focus on decision analysis and cost-effectiveness analysis. Students will learn about alternative approaches of modeling research questions for these fields, including calculation of costs and effectiveness measures using standard modeling methods. The course will also introduces how to compare outputs as a result of decision tree and Markov modeling, and sensitivity analysis.

Course objectives

At the conclusion of this course, students will be able to:

  • Define basic concepts of economic evaluation 

  • Understand different methods and tools of economic evaluation

  • To define the scope of an economic evaluation 

  • To understand how to frame comparators for your audience based on a target population

  • What are the alternatives to a vaccine program?

  • To define the perspectives impacted by a vaccine program

  • To understand how to frame the time horizon of a vaccine program

  • To consider the impact of vaccines on different stakeholders at different time points

  • To differentiate between uses of decision tree and Markov model

  • To identify study designs that contribute to better cost, effectiveness and probability parameter estimates

  • To understand the process of probability extraction from high-quality sources

  • To describe measurement of health gains in terms of health state preference and natural units

  • To provide background on the rationale and importance of decision analysis (DA) and cost-effectiveness analysis (CEA)

  • To explain the theoretical foundations DA/CEA

Schedule

  1. Session 1: Overview of decision analysis and cost-effectiveness

  2. Session 2: Defining the scope of a cost-effectiveness analysis I

  3. Session 3: Defining the scope of a cost-effectiveness analysis II

  4. Session 4: Study design components of economic evaluation

  5. Session 5: Measuring and valuing costs

  6. Session 6: Measuring and valuing health outcomes

  7. Session 7: Reporting and interpreting results of economic evaluation

  8. Session 8: Introduction to decision tree modeling

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