Predicting the broader economic value of pneumococcal vaccination (PCV) in slowing AMR progression in China

Home > Predicting the broader economic value of pneumococcal vaccination (PCV) in slowing AMR progression in China

Antimicrobial resistance (AMR) poses a severe threat to global public health. However, vaccinations have mainly been undervalued as a method to hinder AMR progression.

This study examined the health and economic impact of increasing PCV coverage in China, focusing on the value of PCV in slowing AMR progression. They developed and utilized an agent-based DREAMR (Dynamic Representation of the Economics of AMR) model to simulate PCV coverage, pneumococcal infections, antibiotic use, AMR accumulation, and resulting health and economic outcomes.

While the results are specific to antibiotic utilization for pediatric pneumococcal diseases in China, the DREAMR model could be used to examine the impact of increased PCV coverage on AMR accumulation across various countries utilizing different antibiotics.

  • Primary authorEmber (Yiwei) Lu, University of North Carolina at Chapel Hill
  • LanguageEnglish

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