China has not yet incorporated varicella (chickenpox) vaccination into its National Immunization Program (NIP), resulting in diverse regional vaccination approaches. A publication in the American Journal of Preventative Medicine examined five different immunization scenarios in Shanghai to identify the most effective varicella vaccination strategy, considering both cost-effectiveness and projected costs over a five-year period. The study found that one dose of routine varicella vaccination was the most cost-saving and cost-effective (dominant) scenario. Two doses of the vaccination had the highest QALY and its ICER was below the willingness-to-pay threshold. The authors concluded that a two-dose varicella vaccination strategy targeting 1- and 4-year-old children, with a 95% coverage rate, was the most optimal strategy in Shanghai.
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