Navigating the road to immunization equity: systematic review of challenges in introducing new vaccines into Sub-Saharan Africa’s health systems

Home > Navigating the road to immunization equity: systematic review of challenges in introducing new vaccines into Sub-Saharan Africa’s health systems

A new systematic review in Vaccines documents the barriers to new vaccine introduction in sub-Saharan Africa by distinguishing between vaccines integrated into routine immunization programs and those introduced primarily for outbreak response. The review included 33 articles concerned the introduction of eight new vaccines (malaria vaccine, COVID-19 vaccine, HPV vaccine, Ebola vaccine, cholera vaccine, hepatitis B vaccine, rotavirus vaccine, and typhoid vaccine).

Thematic analysis showed:

  • Coordination and financing challenges for six vaccines in seventeen countries
  • Acceptability challenges for five vaccines in ten countries
  • Logistical challenges for two vaccines in six countries
  • Quality service delivery challenges for three vaccines in thirteen countries. 

Addressing the challenges of introducing new vaccines in sub-Saharan Africa requires targeted, evidence-based strategies. Prioritizing political commitment, innovative funding, public education, workforce development, and infrastructure improvements will strengthen immunization systems and enable timely vaccine delivery. Collaborative efforts and a focus on local context can advance equitable health outcomes, safeguard public health, and support global immunization goals.

How can the findings be used?

The study’s findings can assist governments and international organizations in developing policies to overcome barriers such as financing, logistics, and vaccine hesitancy. National Immunization Programs and NGOs can leverage these insights to enhance vaccine distribution and community engagement. Public health campaigns can be tailored to effectively address misinformation and cultural beliefs. Donors can refine their funding models, and researchers can identify gaps for further study to promote immunization equity.

Thumbnail image credit: WHO / Francisco María Galeazzi

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