A commentary in the Lancet highlights the pivotal role of NITAGs in guiding government decisions on vaccine use, drawing on insights from the Fifth Global National Immunization Technical Advisory Group (NITAG) Network meeting. NITAGs provide independent, evidence-based recommendations vital for successful immunization strategies and are pivotal in guiding outbreak responses during health crises. The COVID-19 pandemic underscored the vital role of NITAGs as primary advisory bodies for vaccine introduction and use in most countries. NITAGs had significant political and time pressures during the pandemic, navigating complex issues like rapidly evolving evidence, data gaps, ethical considerations, and the necessity for frequent adjustments and even off-label recommendations. The pandemic also underscored the value of global networks and interactions with WHO’s Strategic Advisory Group of Experts on Immunization. The increasing availability of new vaccines presents a challenge for NITAGs in prioritizing interventions and target populations, especially with limited financial and programmatic capacities. Strengthening NITAGs through investments in technical support, training, and peer learning is essential for sustainable, country-owned immunization programs.
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