This systematic review and meta-analysis estimated hospital stay length and treatment costs for patients with susceptible and antibiotic-resistant Salmonella Typhi, Paratyphi, and non-typhoidal Salmonella infections. Patients with drug-resistant Salmonella infections had significantly longer hospital stays of additional 0.5 to 2.2 days and incurred higher treatment costs than those with susceptible infections. In low-income settings, drug-resistant typhoidal infections led to an average stay of 8.4 days versus 6.4 days for drug-susceptible cases. Data gaps remain in high-burden regions like sub-Saharan Africa and Asia.
Thumbnail image credit: Study authors
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