This article evaluates effective, cost-effective, and affordable cervical cancer prevention strategies for China, considering the introduction of a domestic 9-valent HPV vaccine and advancements in screening. Using a Markov model, the study analyzed 38 different strategies over 30 years comparing them with no intervention. The researchers found that screening women aged 35–64 with visual inspection with acetic acid (VIA) combined with bivalent vaccination for girls aged 9–14 is currently the most suitable strategy for China, meeting the World Health Organization’s elimination targets, cost-effectiveness thresholds, and affordability criteria. The study indicates that greater financial resources would allow for the adoption of more accurate screening methods and the 9-valent HPV vaccine.
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