This peer-reviewed article reports findings from a cross-sectional survey study assessing pertussis vaccination intentions and vaccine attribute preferences among adolescents, adults, and pregnant women in China. The study used multistage stratified cluster random sampling across five provinces selected to reflect geographic and socioeconomic diversity. Through a discrete choice experiment (DCE), researchers examined preferences for key vaccine attributes, and used multivariable logistic regression and causal mediation analysis to identify correlates of vaccination intention and the role of pertussis knowledge.
Key findings
Respondents across all groups expressed generally high intention to receive pertussis vaccination.
Among adolescents and adults, larger household size was associated with higher vaccination intention, while among pregnant women, primiparity was associated with lower intention.
Pertussis knowledge partially mediated the relationship between education level and vaccination intention.
In the discrete choice experiment, vaccine efficacy was the dominant driver of preference, followed by lower risk of adverse events following immunisation (AEFI), domestic vaccine origin, and lower cost.
Vaccine duration did not significantly influence choices.
Pregnant women demonstrated higher willingness to pay for pertussis vaccination compared with adults.
Preferences varied across demographic and cognitive subgroups, indicating heterogeneity in vaccine decision-making.
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