This new guidance from the World Health Organization (WHO) provides practical support for using mathematical modelling to inform immunization policy and programme decisions. Developed as a joint initiative between WHO and the Immunization and Vaccines-related Implementation Research Advisory Committee (IVIR-AC), the guidance aims to bridge the gap between modelling outputs and real-world policy needs. It is designed as a first-line resource for stakeholders involved in immunization decision-making—including NITAG and RITAG members, EPI managers, and technical partners—supporting them in understanding, interpreting, and applying modelling evidence. The development of this guidance is informed by a qualitative needs assessment of immunization decision-makers and modelers across WHO regions. A related commentary can be read on Vaccine.
Key features
How can this resource be used?
This guidance can help:
How can the findings be used?
Mathematical models are increasingly used to inform decisions on vaccine introduction, delivery strategies, and programme optimization, helping decision-makers explore “what if” scenarios when empirical data are limited. However, translating modelling results into policy remains a challenge. This guidance addresses that gap by supporting countries to better engage with modelling processes and make informed, context-specific decisions.
Thumbnail image credit: WHO
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